An article in molecular pharmaceutics published in 2009 studies the effect of silver nanoparticles on bacteria in a gel based formulation.
In this study the principal use case is for treating burns, but any open wound likely to become infected could be equally treated by using a silver particle c containing gel.

The first paragraph begins “Abstract:
Silver is an effective antimicrobial agent with low toxicity, which is important especially in the treatment of burn wounds where transient bacteremia is prevalent and its fast control is essential. Drugs releasing silver in ionic forms are known to get neutralized in biological fluids and upon long-term use may cause cosmetic abnormality, e.g., argyria and delayed wound healing. Given its broad spectrum activity, efficacy and lower costs, the search for newer and superior silver based antimicrobial agents is necessary. Among the various options available, sil-ver nanoparticles have been the focus of increasing interest and are being heralded as an excellent candidate for therapeutic purposes. “
In other words ionic silver products are not nearly as effective as genuine silver particles, and they carry the potential to be cosmetically detrimental.
In fact almost all studies involving silver as an antimicrobial agent have used silver nanoparticles and NOT IONIC SILVER PREPARATIONS, for this very reason.
Looking at this particular study, there emerges a number of points of interest, these can be summarised as below.
- Silver particles are effective at significantly lower concentrations than other silver containing prod-ucts such as silver sulphadiazine.
- Smaller silver particles were much more effective than larger ones, using 7 to 20 nm and 3 to 7 nm particles.
When compared to the figures in this study MESOSILVER would be shown to be thousands of times more effective.
Mesosilver is the most effective genuine silver colloid available.
Neither Pure Colloids UK nor Purest Colloids USA endorses the use of any of its products in any kind of therapeutic application. The information provided here is simply an commentary on existing pub-lished peer reviewed scientific data.