Mesosilver is the smallest particle size true colloidal silver available: 0.61 Nanometers, 20 ppm concentration. No matter what other manufacturers may say or claim, MesoSilver is the only true sub-nanometer colloid available in the UK.

250ml 20ppm pure colloid silver supplement by Purest Colloids now available online in our UK shop.

Colloidal Silver made with the highest purity, sterile reagent grade deionised water, with no potentially dangerous protein products. Colloidal Silver does not require refrigeration after opening. MesoSilver is non toxic (per Material Data Safety Sheets). NOTE: high PPM (parts per million) does NOT necessarily mean high PSA or bioavailability. Colloidal silver concentration is 20ppm minimum. Please see the purest colloids website for more technical information on colloidal silver and the pitfalls of some other products. It is very important to read and understand why our product is different to competing products. MesoSilver is a registered trademark of Purest Colloids, Inc. World’s Highest Particle Surface Area (PSA), which is up to 600 times greater than other products. NOTE: high PPM (parts per million) does NOT necessarily mean High PSA or Bioavailability.

World’s Smallest Particle Size, less than 1nm on average, High Colloidal/Ionic percentage & High Particle Concentration. Made with the highest purity, sterile reagent grade deionised water, with no potentially dangerous protein products. Exclusive worldwide manufacturer using the Meso-Process. “

Why is silver particle content important?

The benefits of colloidal silver in the human body are produced by the nanometer sized metallic silver particles which release ions not the ions directly. In fact, many researchers believe that silver ions cannot survive in the human for more than a brief instant. One researcher, Dr. Meade, has estimated the half life of a silver ion in the human body as being 7.8 seconds! This is because silver ions readily combine with chloride ions to form silver chloride, which is an insoluble silver compound. Chloride ions are the most prevalent anion in the human body and are found in high concentration due to the sodium and potassium chloride content of human serum.

Does that mean the ionic silver is ‘bad’?

Not at all! While the highly reactive nature of silver ions prevents them from surviving inside the human body due to the chloride ions, silver ions are very effective if there are no chloride ions in the environment. Ionic silver has the ultimate surface area since a silver ion is slightly smaller than an atom of silver. The effectiveness of ionic silver is limited to areas where there are no chloride ions present, which can mean many places outside the human body. Ionic silver is effective when used topically or when nebulised and inhaled. Of course, Mesosilver is also very effective for these same applications due to the large surface area of the silver mesoparticles. Inside the body, Mesosilver particles are not effected by the chloride ions and will circulate in the bloodstream for maximum effectiveness in killing pathogens.

Brown colour of Mesosilver

Unlike most colloidal silver products, Mesosilver is brown in colour, looking like dark iced tea. Previously, it was thought that such a brown colour indicated the presence of large silver particles, which is the case for colloidal silver produced by methods other than the mesoprocess. It is the very high concentration of mesosilver particles, not large particles or contamination, that give Mesosilver its distinctive coloration. The small size of the silver particles is confirmed by the use of a state-of-the-art scientific instrument designed specifically for measuring such small particles called a Photon Correlation Spectrometer(PCS). The PCS used during the development of Mesosilver was manufactured by Malvern Instruments, Ltd. of the United Kingdom, one of the foremost producers of such equipment in the world. The particle size report from the Malvern confirms the claimed size of 0.65 nm for Mesosilver.
Many producers of colloidal silver can only guess at the particle size in their products. Some try to measure the particles with a Transmission Electron Microscope (TEM) which is fraught with problems when trying to measure highly ionic solutions.

The magic combination of properties

Mesosilver combines small particle size and high particle concentration, the magic combination of properties, to produce a colloidal silver product that has the highest particle surface area of any colloidal silver product ever tested. See the graphical representation that compares the surface area of Mesosilver to other products.

Why is silver particle content important?

The benefits of colloidal silver in the human body are produced by the nanometer sized metallic silver particles not the ions. In fact, many researchers believe that silver ions cannot survive in the human for more than a brief instant. One researcher, Dr. Meade, has estimated the half life of a silver ion in the human body as being 7.8 seconds! This is because silver ions readily combine with chloride ions to form silver chloride, which is an insoluble silver compound. Chloride ions are the most prevalent anion in the human body and are found in high concentration due to the sodium and potassium chloride content of human serum.



First, colloidal silver’s ability to control antibiotic-resistant superbugs is astonishing. While employed at UCLA Medical School in the 1980s, Larry C. Ford, MD, documented over 650 different disease-causing pathogens that were destroyed in minutes when exposed to small amounts of silver.
Colloidal silver, unlike its modern prescription antibiotic counterpart, simply doesn’t create resistance or immunity in the organisms that are killed by it. This point cannot be emphasised enough, especially in light of the Centres for Disease Control and Prevention (CDC) recently reporting that more than 2 million people in the U.S. suffer illness every year as a result of antibiotic-resistant infections and 23,000 die from these infections.

Wound Care/Skin Health

Robert O. Becker, MD, says that colloidal silver stimulates healing in the skin and other soft tissues. In a research article produced by Pharmacognosy Communications in 2012, it was specifically recommended that certain colloidal silver preparations should be considered for topical use to treat burns, thrush, periodontitis and other conditions.
For instance, you can treat ringworm (Tinea capitis) at home with colloidal silver because it’s a potent anti-fungal. Caused by a fungus that lives on the top layer of the skin, ringworm presents as round, scaly patches. It’s contagious and spread by skin contact and by contaminated materials, such as clothing.
Colloidal silver benefits many skins conditions such as psoriasis and eczema as well. It’s soothing to scrapes and even repairs tissue damage from burns.

Eye/Ear Infections

Pink eye is an inflamed mucous membrane that covers the eyeball and eyelid lining, and it’s primarily caused by a bacterial or viral infection. Colloidal silver can be used for prompt action against this irritating and highly infectious virus and bacteria.
When applied on the infected eye, the tiny silver colloids pick up the infected cells by attracting them electromagnetically and sending them into the bloodstream to be eliminated.
Our modern prescription antibiotic drugs are designed to work against specific classes of bacteria, but ear infections may be caused by multiple classes of bacteria or can even be fungal.
In this case, the prescription antibiotic will be useless, whereas colloidal silver is effective regardless of what may be causing your infection.


Colloidal silver benefits can be experienced as an anti-viral for pneumonia, herpes, shingles and warts. Dr. Martin Hum, from the Institute for Optimum Nutrition, lists colloidal silver as one of the natural remedies to stop viruses fast.
Colloidal silver suffocates the virus and can even reduce the activity of many difficult to treat viruses. There are also numerous anecdotal accounts of colloidal silver’s efficacy against the hepatitis C virus.


Colloidal silver is also a fantastic anti-inflammatory remedy. Case in point: Researchers at the National Institutes of Health (NIH) studied the effects of inflammation after being treated by colloidal silver; they found that the inflamed skin of pigs treated with silver experienced near-normal skin after 72 hours, while other treatment groups not treated with silver remained inflamed.
Research is beginning to reflect what many people have already known anecdotally for years – that colloidal silver can reduce swelling, speed healing, and boosts cell recovery!


Widely used to control sinus infections, colloidal silver can benefit people as a nasal spray, according to a study published in the International Forum for Allergy and Rhinology last year.
Specifically shown to kill Staph aureus, you can add a few drops of silver in a “neti pot” or by applying directly into your nasal cavity and letting it drain down your throat by tilting your head back.
Also, it’s important to point out that recent research indicates that hidden infections by pathogens could be a cause of respiratory inflammation associated with common allergies and asthma. Colloidal silver destroys Pseudomonas aeruginosa infections, which may be the reason why airborne allergy sufferers often find such dramatic relief from colloidal silver.

Colds and Flu

Some claim that colloidal silver helps prevent all types of flu, including swine flu, as well as the common cold.
Few studies have been done to test this clinically, but in 2011 the NIH took 100 children under the age of 12 suffering from the common cold and nasal congestion and assigned them into two groups; the first group was treated with a solution of colloidal silver and beta glucan, and the second group with saline solution. Even though both groups benefited from the treatment, 90% of the people in the colloidal silver group completely recovered!


Our modern drugs have become limited in their efficacy when it comes to fighting bronchitis or pneumonia. Typically, antibiotics are administered as the first line of defence, but when the pneumonia is viral, antibiotics won’t help in the least. The nice thing about colloidal silver is that it can help regardless of the pathogen.
Colloidal silver is a remarkable product to help fight against bronchitis and pneumonia when ingested internally, but an even more effective way to utilise it? Simply breathe it into your lungs.
This way, the silver directly contacts the germs residing in the lungs, which are causing bronchitis or pneumonia. It’s basically the same thing as using respiratory support, and it works speedily, clearing it up within a couple of days.
Now, the most effective method to get the colloidal silver into the lungs is to use a nebuliser. Generally, use one teaspoon approximately three times a day for 10 to 15 minutes.

What is Colloidal Silver?

Before the invention of the refrigerator, it was common practice to drop a silver coin into a container of milk as a preservative because silver was known to prevent the growth of algae, bacteria and other undesirable organisms.
Dating back to ancient times, silver was also a popular remedy to stop the spread of diseases. Its use as a natural antibiotic continued all the way until the 1940s, when modern antibiotics arrived.
True colloid silver is a suspension of silver nanoparticles in pure water. The effectiveness of any true colloid is determined by particle size, the smaller the particle the more surface area it has.
With the development of the MESO process by Purest Colloids INC, mesosilver has opened a new chapter in the use of colloid silver as a health aid. No other product has a larger surface area to weight ratio, nothing even comes close.

How Colloidal Silver Benefits Work

According to a report written by Richard Davies and Samuel Etris of The Silver Institute in a 1996, there are three primary ways that colloidal silver can help improve health.
Catalytic Oxidation: Silver naturally holds onto oxygen molecules, which readily react with the sulfhydral (H) groups that surround bacterial and viruses. In turn, this helps block the life-preserving cellular process known as cellular respiration, which is defined as “the set of metabolic reactions and processes that take place in the cells of organisms to convert biochemical energy from nutrients into adenosine triphosphate (ATP), and then release waste products.
Reaction with Bacterial Cell Membranes: Silver ions can attach to bacteria cell membranes directly and produce the same respiration-blocking effect.
Binding with DNA: Shown to literally enter bacteria DNA, up to 12% of silver has been detected in Pseudomonas aeruginosa. According to one source, “While it remains unclear exactly how the silver binds to the DNA without destroying the hydrogen bonds holding the lattice together, it nevertheless prevents the DNA from unwinding, an essential step for cellular replication to occur.”

There are basically three types of products that are marketed as ‘colloidal silver’ and these can be categorised as:

  • Ionic silver solutions
  • Silver protein
  • True colloidal silver

Ionic Silver

Ionic silver solutions are products whose silver content primarily consists of silver ions. Although ionic silver is often marketed as colloidal silver, it’s not true colloidal silver. Because it’s the least expensive to produce, ionic silver is the most popular product in this category. The problem? It simply won’t produce the same benefits that true colloidal silver can. These products should not be called colloids silver, they are solutions, a solution cannot be a colloid.

Silver Protein

In order to keep large silver particles suspended, silver protein-based products add gelatin. Silver protein is the second-most popular type of colloidal silver product on the market and can easily be made by adding water to silver protein powder. Again, it’s also often marketed and labeled as colloidal silver, but should not be confused for the real thing. Silver protein is less effective for human use, and you won’t experience the true colloidal silver benefits.

True Colloidal Silver

Lastly, true silver colloids don’t contain any protein or other additives, as the vast majority of the silver content consists of nanometre-sized silver particles. Mesosilver is the most effective of all colloid silver products due to its small particle size of 0.62 of a nanometer.
Particle size is the single most important factor in colloid silver effectiveness, the smaller the particle the greater the surface area.

Colloidal Silver Side Effects

Although the National Centre for Complimentary and Integrative Health reports that colloidal silver may cause poor absorption of some drugs, there is limited research proving that side effects to colloidal silver use even exist. It is reported that using colloid silver in conjunction with antibiotics vastly increases the effectiveness of the antibiotic.
Nonetheless, you may come across many warnings about it causing an irreversible condition called argyria (when people turn blue). However, this is caused by misuse not of true colloidal silver, but through other cheaper products marketed as colloidal silver, such as ionic silver or silver protein.
One point to consider is that, because colloidal silver is such a potent antibacterial agent, you should be sure to supplement with probiotics during sustained use to be sure that you maintain a proper balance of microflora. Infrequent use of small amounts of Mesosilver will not adversely affect intestinal flora.


Avoid storing Mesocolloids at temperatures exceeding 27 deg C Do not freeze Avoid direct sunlight Do not drink directly from the bottle Once decanted do not pour unused liquid back into the bottle.

Shelf Life

Unopened, as long as the above conditions are adhered to, Mesosilver will keep indefinitely. Opened – Use within 1 year.


The dosage for Mesosilver is typically between one teaspoon (5mL) and one tablespoon (15mL) daily to help maintain health. One to four tablespoons taken 4 times per day may be taken to help fortify the immune system when needed. Actual dosage will vary based on individual needs. A 500 mL bottle will provide a one month supply when used at a dosage of one tablespoon per day.